Mitomycin C

 

Name Mitomycin C 
Synonyms [1aR-(1aalpha,8beta,8aalpha,8balpha)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-alpha]indole-4,7-dione; 6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione carbamate (ester)
Molecular Formula C15H18N4O5 
Molecular Weight 334.33 
CAS Registry Number 50-07-7 
Assay:99% 
Molecular formula: C15H18N4O5 
Molecular weight: 334.33 
Appearance: Violet luster crystallization 

Indication: For lung cancer, liver cancer and malignant change Hodgkin's lymphoma, disease, reticular cell sarcoma, uterine cancer, leukemia, colon cancer and pancreatic cancer etc all have certain curative effect. Especially for stomach and breast cancer have good effect. 

Pharmacology:Extracted from chain mold, Mitomycin , it's chemical structure contain benzene hydroquinone and acetyl imine base and ammonia chlorobenzoyl three active groups,and its role similar with alkylation agent. Mitomycin can and DNA chain form crosslinking can make the cell DNA depolymerization, restrain DNA, also have the inhibition to RNA replication. 


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